Figure 4 | Scientific Reports

Figure 4

From: Overactive autophagy is a pathological mechanism underlying premature suture ossification in nonsyndromic craniosynostosis

Figure 4

Effect of rapamycin or wortmannin on autophagic induction during cranial SMC differentiation. (A) Representative western blot of fused and unfused SMCs treated with or without rapamycin or wortmannin at different differentiation time points. (B) Quantification of LC3 and β-actin expression level by densitometry. Full-length blots are presented in the Supplementary Fig. 3. Data are expressed as the mean ± SD of three independent experiments. *P < 0.05; **P < 0.01.

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