Table 1 The Subjects’ Characteristics.

From: Low Bilirubin Levels Indicate a High Risk of Cerebral Deep White Matter Lesions in Apparently Healthy Subjects

 

All

Total Bilirubin

p value

(n = 1121)

Low (n = 83)

Intermediate (n = 818)

High (n = 220)

All

Age, year

62 ± 10

59 ± 11

63 ± 10

61 ± 9

0.001

Male, n (%)

756 (67)

50 (60)

535 (65)

171 (78)

0.001

Height, cm

164 ± 8

164 ± 9

164 ± 9

166 ± 8

0.001

Weight, kg

63 ± 12

65 ± 13

62 ± 12

64 ± 11

0.008

Body Mass Index, kg/m2

23 ± 3

24 ± 4

23 ± 3

23 ± 3

0.002

Systolic Blood Pressure (mmHg)

122 ± 19

120 ± 21

122 ± 19

123 ± 19

0.663

Diastolic Blood Pressure (mmHg)

75 ± 12

74 ± 11

75 ± 12

77 ± 12

0.112

Hypertension, n (%)

242 (22)

19 (23)

178 (22)

45 (20)

0.876

Diabetes Mellitus, n (%)

170 (15)

14 (17)

127 (16)

29 (13)

0.625

Dyslipidemia, n (%)

77 (7)

8 (10)

52 (6)

17 (8)

0.454

Hyperuricemia, n (%)

68 (6)

5 (6)

48 (6)

15 (7)

0.872

Never Smoker, n (%)

675 (60)

45 (54)

489 (60)

141 (64)

0.260

Past Smoker, n (%)

306 (27)

21 (25)

232 (28)

53 (24)

0.412

Current Smoker, n (%)

140 (12)

17 (20)

97 (12)

26 (12)

0.073

Alcohol Consumption

None, n(%)

244 (22)

23 (28)

181 (22)

40 (18)

0.179

1–4 days a week, n (%)

522 (47)

44 (53)

379 (46)

99 (45)

0.445

5 days or more, n (%)

355 (32)

16 (19)

258 (32)

81 (37)

0.014

White Blood Cell, /mm3

5500 ± 1600

5900 ± 1900

5400 ± 1600

5300 ± 1300

0.007

Hemoglobin, g/dl

14.0 ± 1.2

13.4 ± 1.4

13.9 ± 1.2

14.4 ± 1.2

<0.001

Platelet, x103/mm3

220 ± 54

330 ± 58

221 ± 54

213 ± 49

0.030

Albumin, g/dl

4.6 ± 0.3

4.5 ± 0.2

4.6 ± 0.2

4.7 ± 0.3

<0.001

Uric Acid, mg/dl

5.6 ± 1.3

5.5 ± 1.3

5.6 ± 1.3

5.7 ± 1.3

0.231

Creatinine, mg/dl

0.8 ± 0.2

0.9 ± 0.4

0.8 ± 0.2

0.9 ± 0.2

0.932

Total Bilirubin, mg/dl

0.8 ± 0.3

0.4 ± 0.0

0.7 ± 0.1

1.2 ± 0.3

<0.001

Indirect Bilirubin, mg/dl

0.6 ± 0.2

0.3 ± 0.0

0.5 ± 0.1

0.9 ± 0.3

<0.001

Aspartate Transferase, IU/L

22 ± 5

21 ± 6

22 ± 5

22 ± 5

0.060

Alanine Transaminase, IU/L

20 ± 7

20 ± 7

20 ± 7

20 ± 7

0.668

Gamma-Glutamyl Transpeptidase, IU/L

122 ± 70

118 ± 79

119 ± 66

132 ± 77

0.063

Low-Density Lipoprotein Cholesterol, mg/dl

119 ± 28

116 ± 30

120 ± 28

117 ± 29

0.311

High-Density Lipoprotein Cholesterol, mg/dl

60 ± 16

53 ± 14

61 ± 16

61 ± 16

<0.001

Triglyceride, mg/dl

106 ± 65

132 ± 110

105 ± 62

99 ± 50

0.325

Hemoglobin A1c, %

5.8 ± 0.7

5.9 ± 0.7

5.8 ± 0.7

5.7 ± 0.7

0.174

  1. The subjects were divided into three groups according to total bilirubin levels as follows: Low, <0.5 mg/dl; Intermediate, ≥0.5 mg/dl and <1.0 mg/dl; and High, ≥1.0 mg/dl.