Figure 2 | Scientific Reports

Figure 2

From: Endometrial Mesenchymal Stem/Stromal Cells Modulate the Macrophage Response to Implanted Polyamide/Gelatin Composite Mesh in Immunocompromised and Immunocompetent Mice

Figure 2The alternative text for this image may have been generated using AI.

Macrophages surround implanted mesh with or without eMSC. Representative images of F4/80 immunostaining in (A) C57BL/6 mice implanted with eMSC/PA + G mesh (upper panel) and PA + G mesh control (lower panel) for 3–30 days, and similarly implanted in (B) NSG mice. Macrophages (F4/80+, green) are shown as percentage of total nucleated cells in the first 100 µm increment around mesh filament in (C) C57BL/6 mice and in (D) NSG mice. Data are mean ± SEM of n = 6 animals/group and analyzed by two-way ANOVA. m, mesh, g, gelatin, white dashed lines, outline of PA + G mesh, yellow dotted lines show the 100 µm increment around mesh analyzed eg in (A, D7). Arrowheads, representative F4/80 macrophages both within and outside the 100 µm increment around PA + G mesh. Scale bars 100 µm.

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