Table 2 Clinical and laboratory variables at D1 and D7 for the 17 patients, divided in survivors (S, 9 pts) and non-survivors (NS, 8 pts).

From: An Innovative Approach for The Integration of Proteomics and Metabolomics Data In Severe Septic Shock Patients Stratified for Mortality

 

D1

D7

S

NS

S

NS

Heart Rate (bpm)

103.5 ± 28.4

106.1 ± 12.8

80.4 ± 11.0

91.1 ± 8.7

Mean Arterial Pressure (mmHg)

76. 6 ± 18.3

72.0 ± 11.0

96.3 ± 13.8*

78.4 ± 12.0*

Central Venous Pressure (mmHg)

11.4 ± 5.8

11.5 ± 4.4

7.9 ± 5.1

8.8 ± 2.1

Urine output (mL/day)

2556.1 ± 918.4

1840.0 ± 1652.8

3705.6 ± 1580.2*

1737.5 ± 1478.9*

FiO2 (%)

59.7 ± 12.4

56.3 ± 20.8

40.6 ± 8.5

46.3 ± 23.4

ScvO2 (%)

73.3 ± 11.6

78.5 ± 7.5

77.1 ± 7.3

77.9 ± 4.5

PvCO2 (mmHg)

46.8 ± 5.7

47.8 ± 4.9

50.6 ± 5.2

46.5 ± 7.8

PaCO2 (mmHg)

42.3 ± 6.3

44.3 ± 6.4

45.3 ± 3.9

41.6 ± 8.3

PvO2 (mmHg)

43.3 ± 4.6

46.5 ± 7.4

44.1 ± 5.9

44.6 ± 5.9

PaO2 (mmHg)

122.2 ± 61.0

98.5 ± 32.0

126.9 ± 29.8

115.1 ± 61.0

PEEP (cmH2O)

8.5 ± 2.5

5.3 ± 5.4

8.9 ± 2.4

8.6 ± 3.4

Lactate (mmol/L)

3.0 ± 1.6

5.0 ± 2.3

1.4 ± 0.5

2.4 ± 2.2

Platelets (×103/mm3)

63.9 ± 35.4

61.4 ± 68.1

112.0 ± 67.2

80.3 ± 50.9

Creatinine (mg/dL)

2.7 ± 0.9

2.1 ± 1.3

1.8 ± 1.7

1.8 ± 1.5

Biluribin (mg/dL)

1.7 ± 0.9

5.0 ± 4.8

1.9 ± 1.3

9.1 ± 10.8

Presepsin (µg/L)

1486 ± 1256

2673 ± 2351

830 ± 458

4969 ± 5826

Renal Repl Therapy (RRT)[no. (%)]

0 (0%)

2 (25%)

1 (11%)

3 (38%)

Ventilatory Support [no. (%)]

9 (100%)

8 (100%)

4 (44%)

7 (88%)

Sofa score

Overall

11.3 ± 2.4

12.4 ± 3.2

5.0 ± 2.1

9.3 ± 5.1

Respiratory System

2.4 ± 1.0

2.4 ± 1.3

1.2 ± 0.8

1.9 ± 1.0

Coagulation

2.3 ± 0.9

2.5 ± 1.4

1.6 ± 1.1

1.9 ± 1.2

Liver

1.1 ± 0.9

1.9 ± 1.2

1.0 ± 1.0

2 ± 1.8

Cardiovascular System

3.6 ± 0.5

3.6 ± 0.5

0.0 ± 0.0

1.1 ± 1.5

Renal System

1.9 ± 0.6

2.0 ± 1.7

1.2 ± 1.5

2.4 ± 1.8

  1. Data are presented as mean ± SD or as frequency. Mean Arterial Pressure and Urine output (marked with *) at D7 were significantly different between the two groups (p-value < 0.05 Wilcoxon rank-sum test).