Figure 1
Side view of the RyR1-model. The left side is color-coded according to the domains of the receptor. Major domains are the N-terminal domain (
), the handle domains (
), the helical domains (
), the central domain (
) and the channel domain (
). The right side highlights the reduced model, consisting of the central and channel domains, in red. The orange arrow indicates the direction of the calcium current from the SR into the cytoplasm. A top-view is shown in the inset.
