Table 1 Genotype counts and frequencies (%) of SLC6A4 and MAOA variants. P-values are from exact tests of Hardy-Weinberg equilibrium.

From: Appetitive and reactive aggression are differentially associated with the STin2 genetic variant in the serotonin transporter gene

Variant

Genotype

Count (%)

HWE (p-value)

rs25531

AA

209 (72.1)

<0.001

AG

50 (17.2)

GG

31 (10.7)

5-HTTLPR

LL

122 (42.1)

<0.001

LS

160 (55.2)

SS

8 (2.8)

5-HTTLPR-rs25531

L’L’

86 (29.7)

<0.001

L’H’

115 (39.7)

H’H’

89 (30.6)

STin21

12/12

174 (60.0)

0.734

12/10

103 (35.5)

10/10

13 (4.5)

MAOA-uVNTR

MAOA-L

136 (49.4)

0.6604

MAOA-H

139 (50.5)

  1. Abbreviations: 5-HTTLPR: serotonin transporter-linked polymorphic region; MAOA: monoamine oxidase A; HWE: Hardy-Weinberg equilibrium.
  2. 1Alleles are represented as repeats: 12 repeat = 301 bp (high expressing allele); 10 repeat = 267 bp (low-expressing allele).
  3. 2MAOA-L: MAOA-uVNTR low-expressing allele (2-repeat + 3-repeat alleles).
  4. 3MAOA-H: MAOA-uVNTR high-expressing allele (4-repeat + 5-repeat alleles).
  5. 4HWE was calculated based on ungrouped MAOA allele frequencies; individual frequencies are as follows: 291 bp (2-repeat) = 19 (6.9%), 321 bp (3-repeat) = 117 (42.5%), 351 bp (4-repeat) = 134 (48.7%), 381 bp (5-repeat) = 5 (1.8%).
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