Figure 3
Trabecular bone phenotype in control and loaded tibiae in 10 and 22 week-old, and 20 month-old mice. (A) Percent bone volume, trabecular number, separation and thickness. (B) Trabecular thickness heatmap of control and loaded tibiae at various ages. Group sizes were n = 8 for groups1–3 and 4 for group 4 respectively. Group 1: 12 week-old loaded at 11 N; group 2: 22 week-old loaded at 12 N; group 3: 20 month loaded at 9 N and group 4: 20 months old subjected to two episodes of 11 N followed by two weeks of 9 N loading (as in group 3). Box-plots represent means ± SEM. *denotes p ≤ 0.05.
