Figure 1
From: Comparative analyses of whole-genome protein sequences from multiple organisms
(a) Artificial evolution of all open reading frames from Escherichia coli 536. Thirty-two genomes after the fifth generation were used to build the phylogenetic trees shown in b–f. (b,c) Reconstructed trees using all genes evolved in silico using our average sequence similarity method. (b) Distance matrix was constructed with D. (c) Distance matrix was constructed with C. (d–f) Reconstructed trees using a single gene. (d) Tree reconstructed from mutated ECP_0844 genes (404 amino acid length) using our average sequence similarity method developed in this study. (e) Similarity dendrogram constructed from mutated ECP_0844 genes, or (f) mutated ECP_0843 genes (97 amino acid length) using the multiple sequence alignment program ClustalX v. 2.119.
