Figure 5
From: IL-31 is crucial for induction of pruritus, but not inflammation, in contact hypersensitivity

IL-31 is important for pruritus during FITC-induced CHS. (a) Scratching behavior (number of times and duration) in wild-type (n = 12–14) and Il31−/− (n = 12–15) mice was assessed at 24 and 48 hours after challenge with FITC or vehicle alone. The data show the mean + SEM. *p < 0.05 and **p < 0.01.