Table 1 Characteristics of the GERA Cohort, Minority Subjects free of CVD at baseline.

From: Weighted Multi-marker Genetic Risk Scores for Incident Coronary Heart Disease among Individuals of African, Latino and East-Asian Ancestry

Baseline Characteristics

African-American n = 2,089

Latinos n = 4,349

East Asians n = 4,804

Age at Survey, years (mean ± SD) and n (%)

57.1 ± 9.7

55.3 ± 10.2

55.6 ± 10

   30–54

822 (39.3%)

2,066 (47.5%)

2,187 (45.5%)

   55–64

724 (34.7%)

1,308 (30.1%)

1,570 (32.7%)

   65–79

543 (26.0%)

975 (22.4%)

1,047 (21.8%)

Gender, n (%)

   Male

633 (30.3%)

1,192 (27.4%)

1,507 (31.4%)

   Female

1,456 (69.7%)

3,157 (72.6%)

3,297 (68.6%)

Education level, n (%)

   Less than college

275 (13.2%)

1,138 (26.2%)

559 (11.6%)

   College or higher

1,637 (78.4%)

2,831 (65.1%)

3,989 (83.0%)

   Missing

177 (8.5%)

380 (8.7%)

256 (5.3%)

Smoking status, n (%)

   Never

1,239 (59.3%)

2,827 (65.0%)

3,721 (77.5%)

   Former

683 (32.7%)

1,283 (29.5%)

937 (19.5%)

   Current

167 (8.0%)

239 (5.5%)

146 (3.0%)

Alcohol consumption (drinks/week), n (%)

2.5 ± 5.1

2.9 ± 5.2

1.7 ± 3.8

   Abstinence

1,069 (51.2%)

2,049 (47.1%)

3,032 (63.1%)

   Low (<8 in men, <4 in women)

515 (24.7%)

1,119 (25.7%)

957 (19.9%)

   Medium (8–21 in men, 4–14 in women)

310 (14.8%)

828 (19.0%)

500 (10.4%)

   High (>21 in men; >14 in women)

45 (2.2%)

89 (2.0%)

32 (0.7%)

   Missing

150 (7.2%)

264 (6.1%)

283 (5.9%)

   Diabetes mellitus, n (%)

508 (24.3%)

846 (19.5%)

839 (17.5%)

Body mass index, kg/m2 (mean ± SD) and n (%)

29.7 ± 6.4

28.4 ± 6

24.7 ± 4.3

   <18

10 (0.5%)

20 (0.5%)

68 (1.4%)

   18–24.9

443 (21.2%)

1,232 (28.3%)

2,727 (56.8%)

   25–29.9

702 (33.6%)

1,509 (34.7%)

1,382 (28.8%)

   > = 30

815 (39.0%)

1,345 (30.9%)

454 (9.5%)

   Missing

119 (5.7%)

243 (5.6%)

173 (3.6%)

Systolic blood pressure, mmHg (mean ± SD)

128.9 ± 15.6

124.9 ± 15.3

123.0 ± 15.7

Diastolic blood pressure, mmHg (mean ± SD)

76.8 ± 10

74.1 ± 9.9

73.6 ± 10.2

Anti-hypertensives, n (%)

1,187 (56.8%)

1,676 (38.5%)

1,853 (38.6%)

HDL-C, mg/dL (mean ± SD)

55.5 ± 15.1

53.6 ± 14.3

57.5 ± 15

Total Cholesterol, mg/dL (mean ± SD)

190.4 ± 38

195.3 ± 37.2

196.3 ± 36.1

Cholesterol lowering drugs, n (%)

778 (37.2%)

1,408 (32.4%)

1,553 (32.3%)

GFR, mL/min/1.73 m2, (mean ± SD) and n (%)

82.7 ± 19.3

80.2 ± 17.2

80.4 ± 16.9

   <60

197 (9.4%)

399 (9.2%)

389 (8.1%)

   60–90

1,175 (56.2%)

2,754 (63.3%)

3,082 (64.2%)

   > = 90

676 (32.4%)

1,070 (24.6%)

1,161 (24.2%)

   Missing

41 (2.0%)

126 (2.9%)

172 (3.6%)

Framingham Risk Score (median [IQR] and n (%)

6.9 (6.7)

6.0 (6.5)

5.6 (5.8)

   Low (<10%)

1,497 (71.7%)

3,262 (75.0%)

3,791 (78.9%)

   Intermediate-Low (10–15%)

332 (15.9%)

627 (14.4%)

597 (12.4%)

   Intermediate-High (16–20%)

141 (6.7%)

249 (5.7%)

233 (4.9%)

   High (>20%)

119 (5.7%)

211 (4.9%)

183 (3.8%)

Family history of angina/heart attack, n (%)

   No

1,552 (74.3%)

3,227 (74.2%)

3,750 (78.1%)

   Yes

507 (24.3%)

1,089 (25.0%)

1,011 (21.0%)

   Missing

30 (1.4%)

33 (0.8%)

43 (0.9%)

  1. CVD denotes cardiovascular disease; GFR denotes glomerular filtration rate; IQR denotes interquartile range.