Figure 1

Drosophila lacking ion channel mutants with high sensitivity to PQ. (A) Bar graphs representing the survival of Drosophila ion channel mutants normalized to male wild-type (Canton-S) flies. Black bars represent males and gray bar represent females. Two way ANOVA was performed and statistical significance (p < 0.05) are indicated by an asterisk. HisCl1, Trp A1 and GlurRIIA female mutant flies, and Ir64a, Hk and NaCP60E mutant male flies were not sensitive to PQ. (B) Line graphs represent the survival of ion channel mutant flies subjected to 20 mM PQ.