Figure 6
From: Facile Tumor Spheroids Formation in Large Quantity with Controllable Size and High Uniformity
The drug effect on HCT116 tumor spheroids by APH assay. Similar size spheroids (diameter ~500 µm) were treated with different concentrations of Paclitaxel and Doxorubicin for 72 h, and (A) shows a typical controlled spheroid, while (B) shows a spheroid that was treated by 500 nM Paclitaxel for 72 h. More detailed images can be found in Fig. S10. Drug effects of Paclitaxel (C) and Doxorubicin (D) in spheroids cultures, with comparison to monolayer cell cultures. Dose-response curves were plotted exponentially. Scale bars = 200 µm.
