Table 2 Heritability of BMD in the OOA.

From: Evaluation of WISP1 as a candidate gene for bone mineral density in the Old Order Amish

Skeletal BMD

Overall

Male

Female

h2 ± SE

h2_p

h2 ± SE

h2_p

h2 ± SE

h2_p

TH-BMD

0.62 ± 0.05

1.96 × 10−39

0.53 ± 0.09

1.65 × 10−8

0.61 ± 0.09

2.08 × 10−16

HFN-BMD

0.58 ± 0.06

3.66 × 10−32

0.55 ± 0.09

3.12 × 10−8

0.59 ± 0.09

2.11 × 10−13

HIT-BMD

0.62 ± 0.05

2.72 × 10−39

0.56 ± 0.09

6.51 × 10−9

0.59 ± 0.09

8.07 × 10−16

HTC-BMD

0.61 ± 0.06

4.87 × 10−38

0.52 ± 0.09

3.03 × 10−9

0.56 ± 0.09

1.12 × 10−14

LS-BMD

0.66 ± 0.05

9.20 × 10−39

0.51 ± 0.09

7.23 × 10−10

0.67 ± 0.09

1.61 × 10−16

  1. TH-BMD: total hip BMD; HIT-BMD: hip intertrochanter BMD; HFN-BMD: hip femoral neck BMD; HTC-BMD: hip trochanter BMD; LS-BMD: lumbar spine BMD; SE: standard error of h2; p: p value, Covariance including study, sex, age and family structure.
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