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Figure 1

From: Probiotic Lactobacillus fermentum strain JDFM216 stimulates the longevity and immune response of Caenorhabditis elegans through a nuclear hormone receptor

Figure 1

(A) Enhanced lifespan of C. elegans fer-15;fem-1 via conditioning with Lactobacillus fermentum strain JDFM216 for 24 h prolonged the lifespan of C. elegans nematodes. Survival statistics: p = 0.0148 for L1 stage (left), and p = 0.0087 for L4/young adult stage (right) of nematodes compared with worms feeding on the E. coli OP50 control strain (n = 30 per plate). (B) Immune stimulation of C. elegans via pre-conditioning with JDFM216 for 24 h prolonged the lifespan of C. elegans strains, N2 wild-type or pmk-1 mutant infected with S. aureus strain RN6390. Survival statistics: p = 0.0026 for 1 day, p = 0.0492 for 3 days, p = 0.0000 for 6 days, and p = 0.0103 for 9 days conditioned nematodes compared with worms feeding on the E. coli OP50 control strain (n = 30 per plate).

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