Table 1 Diagnostic Performance of CCTA in calcified plaques
De-blooming algorithm | STND | HD STND | |||
|---|---|---|---|---|---|
− | + | − | + | ||
Detection of ≥50% Stenosis | Sensitivity, % (95% CI) | 100(85.9–100) | 100(85.9–100) | 100(85.9–100) | 100(85.9–100) |
Specificity, %(95% CI) | 45.8(26.2–66.8) | 75.0(52.9–89.4) | 62.5(40.8–80.4) | 83.3(61.8–94.5) | |
PPV, %(95% CI) | 69.8(53.7–82.3) | 83.3(66.5–93.0) | 76.9(60.3–88.3) | 88.2(71.6–96.2) | |
NPV, %(95% CI) | 100(67.9–100) | 100(78.1–100) | 100(74.7–100) | 100(80.0–100) | |
Detection of ≥70% Stenosis | Sensitivity, %(95% CI) | 100(69.9–100) | 100(69.9–100) | 100(69.9–100) | 100(69.9–100) |
Specificity, %(95% CI) | 52.3(36.6–67.7) | 64.3(48.0–78.0) | 59.5(43.4–74.0) | 76.2(60.2–87.4) | |
PPV, %(95% CI) | 37.5(21.7–56.3) | 44.4(26.0–64.4) | 41.4(24.1–60.9) | 54.6(32.7–74.9) | |
NPV, %(95% CI) | 100(81.5–100) | 100(84.5–100) | 100(83.4–100) | 100(86.7–100) | |