Table 1 Diagnostic Performance of CCTA in calcified plaques

From: Blooming Artifact Reduction in Coronary Artery Calcification by A New De-blooming Algorithm: Initial Study

 

De-blooming algorithm

STND

HD STND

+

+

Detection of ≥50% Stenosis

Sensitivity, % (95% CI)

100(85.9–100)

100(85.9–100)

100(85.9–100)

100(85.9–100)

Specificity, %(95% CI)

45.8(26.2–66.8)

75.0(52.9–89.4)

62.5(40.8–80.4)

83.3(61.8–94.5)

PPV, %(95% CI)

69.8(53.7–82.3)

83.3(66.5–93.0)

76.9(60.3–88.3)

88.2(71.6–96.2)

NPV, %(95% CI)

100(67.9–100)

100(78.1–100)

100(74.7–100)

100(80.0–100)

Detection of ≥70% Stenosis

Sensitivity, %(95% CI)

100(69.9–100)

100(69.9–100)

100(69.9–100)

100(69.9–100)

Specificity, %(95% CI)

52.3(36.6–67.7)

64.3(48.0–78.0)

59.5(43.4–74.0)

76.2(60.2–87.4)

PPV, %(95% CI)

37.5(21.7–56.3)

44.4(26.0–64.4)

41.4(24.1–60.9)

54.6(32.7–74.9)

NPV, %(95% CI)

100(81.5–100)

100(84.5–100)

100(83.4–100)

100(86.7–100)

  1. PPV, positive predictive value; NPV, negative predictive value; CI, confidence interval; STND: standard mode reconstruction; HD STND: high definition mode reconstruction.