Table 2 Measures of linkage disequilibrium between variants at the APOE locus.

From: Lack of genetic support for shared aetiology of Coronary Artery Disease and Late-onset Alzheimer’s disease

 

rs6857

rs429358

rs7412

rs4420638

rs6857

1.00 (1.00)

0.64 (0.82)

0.01 (0.71)

0.42 (0.74)

rs429358

 

1.00 (1.00)

0.01 (0.68)

0.66 (0.95)

rs7412

  

1.00 (1.00)

0.02 (1.00)

rs4420638

   

1.00 (1.00)

  1. Linkage disequilibrium estimates taken from European 1000 Genomes for variants within the APOE locus: r2 and D′ (in brackets). Variants shown are as follows: rs6857: Peak variant from the IGAP meta-analysis, rs429358: Variant comprising the APOE ε4 allele, rs7412: Variant comprising the APOE ε2 allele, rs4420638: Peak variant from the CARDIoGRAMplusC4D meta-analysis.
Back to article page