Figure 5 | Scientific Reports

Figure 5

From: Additional mitochondrial DNA influences the interactions between the nuclear and mitochondrial genomes in a bovine embryo model of nuclear transfer

Figure 5

Effects of mtDNA supplementation alone on gene expression of miNT embryos when compared with SCNT blastocysts derived from depleted cells cultured in the presence of TSA (n = 3 to 4/group). (a) PANTHER biological process classification. (b) List of the top five biological functions. (c) Gene interaction network involved in cell cycle, cell death and survival, and DNA replication, recombination, and repair. Upregulated and downregulated genes are represented in red and green, respectively. The intensity of colour represents the degree of regulation. Colourless or grey nodes are genes involved in the network which were obtained from the Ingenuity Knowledge Base. The solid and dashed lines represent direct and indirect interactions, respectively.

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