Figure 4 | Scientific Reports

Figure 4

From: OSM-9 and an amiloride-sensitive channel, but not PKD-2, are involved in mechanosensation in C. elegans male ray neurons

Figure 4

OSM-9, but not PKD-2, is involved in touch-induced calcium responses in RnB neurons. (a,b) Averaged calcium responses (a) and maximum ΔF/F0 changes (b) in R1B-R3B neurons induced by mechanical stimulation of 15 μm displacement at the position of rays 1–3 in wild type, pkd-2(sy606) mutants, osm-9(ky10) mutants, and pkd-2(sy606);lov-1(sy582) double mutants. Solid lines show the average fluorescence changes and the shading indicates SEM. (c) Half-maximum response times of touch induced-calcium responses in R1B-R3B neurons in wild types, pkd-2(sy606) mutants, osm-9(ky10) mutants, and pkd-2(sy606);lov-1(sy582) double mutants. n ≥ 12. Data are mean ± SEM. *P < 0.05, unpaired Student’s t-tests.

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