Table 3 Results of salivary cortisol, alpha-amylase and miRNAs.

From: Stress-associated changes in salivary microRNAs can be detected in response to the Trier Social Stress Test: An exploratory study

 

T1

T5

T8

T9

d

Cortisol (μg/dl)**

0.19

0.11–0.22

0.23

0.13–0.48

T1

0.24

0.12–0.41

0.18

0.11–0.29

T5, T8

0.8216

α-Amylase (U/ml)***

69

39–130

178

94–233

T1, T8, T9

93

40–127

80

35–105

2.5182

miRNA16 (ΔCT)*

−0.37

−1.14–0.38

−0.75

−1.83–0.53

−0.17

−0.66–0.53

0.00

−0.49–0.55

T5

0.6796

miRNA20b (ΔCT)##

2.74

1.26–5.22

2.11

1.40–2.53

T1

2.74

1.63–4.10

1.85

0.51–3.64

T1

0.7103

miRNA21 (ΔCT)**

−0.82

−1.77–0.74

−0.39

−1.45–0.36

0.57

−0.55–1.08

T1, T5

0.67

−1.04–1.64

T1, T5

0.8563

miRNA26b (ΔCT)###

0.85

−0.77–2.08

0.11

−0.45–1.44

1.46

0.26–2.32

T5

1.08

−0.07–2.59

1.1236

miRNA29a (ΔCT)

−0.37

−1.59–0.62

−0.86

−1.63–0.31

−0.50

−1.45–1.13

−0.08

−1.59–1.41

0.2768

miRNA134 (ΔCT)#

1.79

1.25–3.11

1.47

0.40–2.34

2.62

1.41–3.52

T5

2.80

0.31–3.23

0.6622

  1. Median and IQR of parameters assessed at times T1, T5, T8, T9 and ‘Cohen d’ effect size.
  2. *pFriedman = 0.059; **pFriedman < 0.05; ***pFriedman < 0.001.
  3. #pSkillings-Mack = 0.068; ##pSkillings-Mack < 0.05; ###pSkillings-Mack < 0.001.
  4. The first row lists median, the second row lists the 25%- and 75%- percentile (IQR). The lowermost row of each parameter lists significant differences to other time points (p < 0.05). (Remark: ΔCT-values are inverse to miRNA-concentrations in the samples: low ΔCT-values indicate high miRNA concentrations/high ΔCT-values indicate low miRNA concentrations).