Figure 2

Changes in nuclear size and shape upon acquired TMZ resistance. (a) Quantification of nuclear area by pixel size. AU = arbitrary units. Two-tailed t-test 42MBGA p = 0.0035; 8MBGA p = 0.0034. (b) Representative image of nuclear size, quantified in a. Change in nuclear structure in 42MGBA-TMZres in comparison to 42MBGA-WT.