Figure 2 | Scientific Reports

Figure 2

From: Perlecan, a heparan sulfate proteoglycan, regulates systemic metabolism with dynamic changes in adipose tissue and skeletal muscle

Figure 2

The mass of white adipose tissue is reduced in Hspg2−/−-Tg mice. (a) Macroscopic images of visceral fat deposition and adipose tissues of the WT-Tg (upper panels) and the Hspg2−/−-Tg (lower panels) mice at 16 weeks of age. The right-hand image of each panel represents brown adipose tissue (interscapular fats, upper row) and visceral adipose tissue (epididymal fats, bottom row). (b–e) Comparisons of tissue weight of (b) visceral adipose tissue (VAT), (c) brown adipose tissue (BAT), (d) liver, and (e) skeletal muscle (quadriceps) in mice at 16 weeks of age fed the different diets. Data points and error bars represent the mean ± S.D. (n = 7). Data were analyzed by two-way ANOVA with Tukey’s multiple comparison. *p < 0.05, ***p < 0.001, ****p < 0.0001. Scale bar, 1 cm.

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