Table 1 Characteristics of maternal exposure and reproduction.

From: Intrauterine smoke exposure deregulates lung function, pulmonary transcriptomes, and in particular insulin-like growth factor (IGF)-1 in a sex-specific manner

 

AIR

CS

p-value

Urine cotinine [mg/ml]#*

(n)

117 ± 26

7

600 ± 25

15

<0.0001

Co-Hb [%] #*

(n)

1.3 ± 0.2

17

6.3 ± 0.6

22

<0.0001

Pregnancy rate [%]

(n)

13.1 ± 8.8

32

9.6 ± 6.9

29

0.3

Pregnancy duration [d]

(n)

19.8 ± 0.5

12

19.8 ± 0.6

12

>0.99

Litter size

(n)

6.2 ± 1.8

32

5.7 ± 1.9

29

>0.99

Visible resorptions

(n)

0.5 ± 0.6

20

1.0 ± 0.5

17

0.1

Male offspring [%]

(n)

43.2 ± 10.2

77

51.3 ± 23.0

72

0.3

Maternal weight at section [g]

(n)

34.4 ± 2.1

15

32.8 ± 2.4

8

0.1

  1. #Mean ± SD, *analyzed in non-pregnant animals; Pregnancy rate: percentage of female mice with successfully established pregnancy after overnight 1:1 mating.
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