Figure 3
From: TDP-43 regulation of stress granule dynamics in neurodegenerative disease-relevant cell types
TDP-43 is required for SG assembly in astrocytes. (A) Representative images of primary astrocytes transfected with TDP-43 siRNA (siTDP-43 #2) and exposed to SA with cytoplasmic SGs marked with an oligo(dT) probe. Scale bar, 10 µm. (B) Number of SGs per cell and (C) size of individual SGs measured at the indicated time points post-SA exposure (n = 3, N = 10). Data is expressed as the mean ± SEM; Student t test *p < 0.05, **p < 0.01, ns: not significant.
