Figure 3
From: Identification of new EphA4 inhibitors by virtual screening of FDA-approved drugs
Molecular docking poses of five drugs in the cavity. Ligand-binding domain of EphA4 (a), and the docking conformations of ergoloid (b), cyproheptadine (c), nilotinib (d), abiraterone (e), and retapamulin (f) in the binding sites. The conformations with the lowest docking energy were selected for demonstration. The proteins are shown in surface representation (b–f), whereas drugs are shown as sticks.
