Table 1 Baseline characteristics of the study population according to Gensini score tertiles.
Overall(n = 1602) | Gensini score category | p | |||
|---|---|---|---|---|---|
<26 (n = 514) | 26–43 (n = 549) | ≥44 (n = 539) | |||
Clinical characteristics | |||||
Age, years | 62.4 ± 10.6 | 61.3 ± 10.6 | 62.4 ± 10.1 | 63.6 ± 10.9 | 0.003 |
Gender (male), % (n) | 67.2 (1077) | 58.6 (301) | 70.1 (385) | 72.5 (391) | <0.001 |
BMI, kg/m2 | 24.8 ± 3.1 | 24.8 ± 3.1 | 24.7 ± 3.1 | 24.8 ± 3.0 | 0.743 |
Systolic pressure, mm Hg | 135 ± 20 | 135 ± 20 | 134 ± 20 | 135 ± 19 | 0.964 |
Diastolic pressure, mm Hg | 78 ± 12 | 78 ± 13 | 78 ± 12 | 77 ± 12 | 0.075 |
Hypertension, % (n) | 58.4 (935) | 56.6 (291) | 58.7 (322) | 59.7 (322) | 0.581 |
Diabetes mellitus, % (n) | 23.2 (371) | 19.8 (102) | 23.3 (128) | 26.2 (141) | 0.052 |
Current smoking, % (n) | 31.1 (499) | 25.1 (129) | 33.3 (183) | 34.7 (187) | 0.001 |
Family history of premature CAD | 57 (3.6) | 17 (3.3) | 18 (3.3) | 22 (4.1) | 0.723 |
LVEF, % | 61.1 ± 6.9 | 60.9 ± 6.9 | 61.1 ± 6.9 | 61.4 ± 7.0 | 0.501 |
Biochemistry parameters | |||||
Lp(a), mg/L | 134 (70–276) | 120 (65–225) | 120 (65–258) | 166 (80–347) | <0.001 |
TC, mmol/L | 4.56 ± 1.08 | 4.50 ± 1.02 | 4.51 ± 1.03 | 4.67 ± 1.17 | 0.018 |
LDL-C, mmol/L | 2.61 ± 0.87 | 2.57 ± 0.85 | 2.54 ± 0.86 | 2.72 ± 0.90 | 0.001 |
HDL-C, mmol/L | 1.14 ± 0.32 | 1.15 ± 0.32 | 1.14 ± 0.33 | 1.14 ± 0.30 | 0.760 |
TG, mmol/L | 1.45 (1.03–2.07) | 1.51 (1.04–2.10) | 1.41 (1.01–2.03) | 1.46 (1.03–2.06) | 0.442 |
non-HDL-C, mmol/L | 3.42 ± 1.03 | 3.35 ± 0.98 | 3.37 ± 0.97 | 3.53 ± 1.12 | 0.009 |
Fasting glucose, mmol/L | 6.08 ± 2.16 | 5.79 ± 1.87 | 6.12 ± 2.06 | 6.33 ± 2.47 | <0.001 |
