Figure 2 | Scientific Reports

Figure 2

From: Oncotically Driven Control over Glycocalyx Dimension for Cell Surface Engineering and Protein Binding in the Longitudinal Direction

Figure 2

Changes in the physical parameters of RBC’s following polymer grafting under crowded and non-crowded conditions. (a) Impact of macromolecular grafting method (non-crowded vs crowding treament) on the number of HPG molecules grafted per RBC, quantified using the tritium (3H) radiolabeled HPG. (b) Electrophoretic drag consequential to increased polymer grafting on cell surface. Circles represent experimental data of RBC movement in an electric field. Lines represent mathematical simulation to predict electrophoretic mobility of RBCs when polymer molecules differ in their distribution along the glycocalyx. (c) Partitioning of HPG-grafted RBCs in PEG-dextran aqueous two-phase partitioning system. Control RBCs are in the lower dextran phase, and those grafted with HPGs move towards the upper PEG phase. Unpaired comparisons using a non-parametric t-test are significant at p < 0.05 (*).

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