Figure 2
Neural dynamics of sensory representation in the PPC. (A) Left, 2-photon image of a FOV with neurons expressing the GECI YC-Nano140. Right, calcium transients from the ROIs selected in the left panel in response to the presented auditory cues and textures, along with the neuropil (NP) signals and the corresponding whisker angles (Wh) in green. The transients represent the very first 5 trials that the mouse has been exposed to. The averaged responses correspond to: texture graininess, P100, n = 57; texture graininess, P1200, n = 26; Catch, n = 17 trials. (B) Example average calcium transients of neurons classified as cue-responsive, touch-responsive, mixed-responsive, suppressed and unclassified. Traces are averages of 40 to 60 P100 trials and corresponding Catch-trials. (C) Pie Chart illustrating the percentage-wise classification of trial-active neurons and the corresponding distribution of Catch-responsive neurons across the classes (darker slice shade; percentage fractions in brackets). Shaded areas around the mean calcium transients correspond to the standard error of the mean (s.e.m.) here and in all subsequent figures.
