Figure 1
From: MicroRNA and transcriptome analysis in periocular Sebaceous Gland Carcinoma
Shared microRNAs in nodular and pagetoid sebaceous gland carcinoma (SGC). (A) Thirty-nine significant differentially expressed microRNA shared between both subtypes using a p < 0.05 threshold. (B) Top 4 differentially expressed miRNAs present in both nodular and pagetoid SGC when compared to tarsal plate control. (C) MicroRNA verification of expression using Taqman RT-qPCR in SGC. Relative expression levels were determined for nodular and pagetoid SGC using Taqman RT-qPCR against normal eyelid tissue for miRNA (i) 34a-5p and (ii) 16-5p. (D) Expression of target genes in both nodular and pagetoid subtypes. Significance levels are shown as *P < 0.05, **P < 0.01, ***P < 0.001. Error bars represent mean +/− s.d.
