Figure 2 | Scientific Reports

Figure 2

From: Establishing quasi-steady state operations of microphysiological systems (MPS) using tissue-specific metabolic dependencies

Figure 2

Identifying MPS-specific nutrient needs. Spent media components were profiled for gut MPS, cardiac MPS and liver MPS over six days. Changes in normalized medium component concentrations (spent medium/fresh medium) for all MPSs (black triangles: gut; red squares: liver; blue circles: cardiac; symbols represent average over three biological replicates) were evaluated at day 2 (a), day 4 (b) and day 6 (c). Changing lactate levels were plotted separately for visual purposes (d). Concentrations of components in spent media were normalized to fresh media concentrations such that values below 1 indicate net consumption and above 1 indicate net production.

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