Table 1 Clinical characteristics of pregnant women and new-borns.

From: Maternal supraphysiological hypercholesterolemia associates with endothelial dysfunction of the placental microvasculature

Variables

MPH (n = 12)

MSPH (n = 8)

Maternal variables

Age (years)

30.6 ± 1.4 (19–36)

30 ± 1.9 (25–39)

Height (cm)

161 ± 1.6 (152–168)

161 ± 1.9 (156–167)

Weight at delivery (kg)

74.4 ± 2.1 (61–85)

72 ± 3.8 (64–89)

BMI at delivery (kg/m2)

29.4 ± 1 (27–30)

28.5 ± 1.9 (23–30)

Mean arterial pressure at delivery (mmHg)

83.7 ± 1.8 (77–97)

82.8 ± 2.7 (70–91)

Basal glycemia (mg/dL)

76.7 ± 2 (68–84)

76.5 ± 3.5 (73–80)

OGTT (mg/dL)

  Basal glycemia

77.4 ± 1.6 (73–82)

76.5 ± 3.5 (73–80)

  Glycemia 2 h after glucose

97.0 ± 4.4 (87–112)

99.5 ± 14.5 (85–114)

Lipid levels at delivery (mg/dL)

  Total cholesterol

234.6 ± 33 (183–275)

331 ± 16* (295–356)

  HDL

64.4 ± 16 (48–100)

61 ± 12 (49–80)

  LDL

117 ± 26 (80–150)

190.1 ± 39* (129–227)

  VLDL

62.6 ± 28 (36–132)

58.4 ± 25 (49–68)

Triglycerides

246.9 ± 93 (80–426)

292 ± 50 (244–342)

New-born variables

Sex (female/male)

7/5

4/4

Gestational age (weeks)

39.3 ± 0.4 (37–41)

39.1 ± 0.7 (37–41)

Birth weight (grams)

3536 ± 140 (2580–4170)

3490 ± 144 (2900–4000)

Height (cm)

51.2 ± 0.8 (45–54)

52.2 ± 0.8 (50–56)

Ponderal index (grams/cm3 × 100)

2.63 ± 0.08 (2.22–3.11)

2.45 ± 0.08 (2.07–2.76)

  1. Women with maternal physiological (MPH, TC < 280 mg/dL) or supraphysiological hypercholesterolemia (MSPH, TC ≥ 280 mg/dL) at delivery were included (see Methods). Weight, body mass index (BMI), blood pressure and lipid profiles were determined at delivery. OGTT, oral glucose tolerance test. HDL, high-density lipoproteins; LDL, low-density lipoproteins; and VLDL, very-low-density lipoproteins. *P < 0.05 versus corresponding values in the MPH group. Data are presented as the mean ± S.D. (range).
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