Figure 6 | Scientific Reports

Figure 6

From: Temporary microglia-depletion after cosmic radiation modifies phagocytic activity and prevents cognitive deficits

Figure 6

Analyses of phagocytic markers in microglia. MFI was used to compare the phagocytic marker levels in microglia. (A,B) Comparison of LAMP-1 (CD107a) MFI by intracellular staining in microglia. PLX5622 treatment caused significantly reduced CD107a compared to the 50 cGy group, *p < 0.05, One-way ANOVA with Sidak’s multiple comparisons test. (C,D) Comparison of CD206 MFI by intracellular staining in microglia. (E,F) Comparison of CD45 MFI by surface staining on microglia. There is no difference in microglial CD45 levels between groups. N = 3–4 each group.

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