Table 2 Analysis of correlations between 25(OH)D₂ and 25(OH)D₃ levels and lymphocyte subsets in elderly patients with age-related illness.

Patient group	Immune marker	25(OH)D₃		25(OH)D₂		Total 25(OH)D
Patient group	Immune marker	r	P	r	P	r	P
CRVD (N = 2,775)	CD8	−0.04	0.03	−0.00	0.98	−0.04	0.04
	CD19	0.04	0.04	−0.04	0.05	0.02	0.25
CAD (N = 2,174)	CD8	−0.05	0.03	0.13	<0.001	0.03	0.14
	CD4	0.02	0.25	−0.07	0.001	−0.02	0.42
	CD19	0.00	0.97	−0.09	<0.001	−0.05	0.03
	CD4/CD8	0.03	0.16	−0.04	0.045	0.003	0.87
T2DM (N = 1,512)	CD8	−0.13	<0.001	−0.02	0.52	−0.13	<0.001
	CD3	−0.09	0.001	−0.002	0.95	−0.09	0.001
	CD19	0.08	0.002	−0.01	0.75	0.08	0.003
	CD4/CD8	0.06	0.01	0.01	0.66	0.07	0.01
Hypertension (N = 1,292)	CD8	−0.07	0.01	0.02	0.47	−0.06	0.03
	CD3	−0.08	0.01	0.01	0.61	−0.07	0.01
	CD19	0.12	<0.001	−0.04	0.17	0.11	0.001
	CD4/CD8	0.06	0.02	−0.00	0.95	0.06	0.03
Kidney disease (N = 141)	CD3	—	—	0.17	0.049	0.12	0.20
	CD4/CD8	0.18	0.03	—	—	0.15	0.08
Digestive disease (N = 143)	CD4	—	—	−0.29	0.001	−0.13	0.11
	CD8	—	—	0.27	0.001	0.16	0.06
Osteoporosis/fracture (N = 127)	CD8	−0.19	0.03	—	—	−0.18	0.043

Note: CD 56 was not included in the table due to missing significant correlations with 25(OH)D₂ or 25(OH)D₃ or total 25 (OH)D; CAD, coronary disease; CRVD, cerebrovascular disease; T2DM, type 2 diabetes mellitus; 25(OH)D₂, 25-hydroxyvitamin D₂; 25(OH)D₃, 25-hydroxyvitamin.

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