Table 1 Substrate specificity and mode of action.
From: Ancient acquisition of “alginate utilization loci” by human gut microbiota
Locus | Strain | Preferred substrate | End products (Mode of action) | Other substrates | End products (Mode of action) |
|---|---|---|---|---|---|
Subfamily 1 | |||||
Acid4041 | “Candidatus Solibacter usitatus” | Hyaluronan | DP2, DP4 (Endo) | ||
OPIT5_27565 | Opitutaceae bacterium TAV5 | Poly-glucuronic acid | |||
Bacint01566 | Bacteroides intestinalis | n.d. | |||
Ypes3069 | Yersinia pestis Z176003 | n.d. | |||
Yent36911 | Yersinia enterocolitica subsp. palearctica Y11 | n.d. | |||
Subfamily 2 | |||||
Pedsa1196 | Pedobacter saltans | Poly-M | Δ** (Exo) | Poly-MG | Δ (Exo) |
Mase04140 | Alteromonas macleodii | Poly-M | Δ (Exo) | Poly-MG/Poly-G | Δ (Exo) |
Alg17c | Saccharophagus degradans 2–40 | Poly-M | Δ (Exo) | ||
Valg4459 | Vibrio alginolyticus | n.d. | |||
Valg4460 | Vibrio alginolyticus | n.d. | |||
Bacegg03249 | Bacteroides eggerthii | Poly-M | Δ (Exo) | ||
Patl3651 | Pseudoalteromonas atlantica T6c | Poly-M | Δ (Exo) | ||
Nonul2377 | Nonlabens ulvanivorans | Poly-M | Δ (Exo) | ||
AlyII31 | Pseudomonas sp. OS-ALG-9 | Poly-M* | n.d. | ||
AlgL32 | Sphingomonas sp. MJ-3 | Poly-M* | n.d. | Poly-MG/Poly-G | n.d. |
OalY1, OalY233 | Halomonas sp. | Poly-M* | Δ (Exo) | ||
Alg17c26 | Saccharophagus degradans 2–40 | Oligo-alginates | Δ (Exo) | ||
AlgL34 | Stenotrophomas maltophilia KJ-2 | Poly-M*, Oligo-alginates | n.d. | ||
Smlt260235 | Stenotrophomonas maltophilia K279a | Poly-M* | Δ (Exo) | ||
OalB51 | Vibrio splendidus 12B01 | Poly-MG* | n.d. | ||
OalC51 | Vibrio splendidus 12B01 | Poly-M | n.d. | ||
OalS1752 | Shewanella sp.Kz7 | Poly-M | n.d. | ||
