Table 2 Baseline characteristics of the StenoCardia cohort, which served as application cohort for the adjustment model development based on the DETECT cohort.
From: Adjusted Troponin I for Improved Evaluation of Patients with Chest Pain
n | All patients | non-AMI | AMI | p-values |
|---|---|---|---|---|
1818 | 1405 | 413 | ||
Male sex (%) | 1208/1818 (66%) | 894/1405 (64%) | 314/413 (76%) | <0.001 |
Age, y, mean (SD) | 61.4 (13.5) | 60.7 (13.9) | 64 (11.8) | <0.001 |
Hypertension | 1339/1818 (74%) | 1026/1405 (73%) | 313/413 (76%) | 0.291 |
Dyslipidemia | 1328/1818 (73%) | 1017/1405 (72%) | 311/413 (75%) | 0.266 |
Diabetes mellitus | 344/1816 (19%) | 250/1404 (18%) | 94/412 (23%) | 0.027 |
Obesity (BMI ≥ 30) | 469/1694 (28%) | 360/1305 (28%) | 109/389 (28%) | 0.918 |
Smoking | 454/1814 (25%) | 305/1402 (22%) | 149/412 (36%) | <0.001 |
Former Smoking | 582/1740 (33%) | 444/1352 (33%) | 138/388 (36%) | 0.346 |
Family history of MI | 632/1814 (35%) | 496/1402 (35%) | 136/412 (33%) | 0.408 |
History of MI | 434/1813 (24%) | 334/1401 (24%) | 100/412 (24%) | 0.909 |
Known CAD | 679/1816 (37%) | 533/1403 (38%) | 146/413 (35%) | 0.359 |
CRP, mg/L, median (IQR) | 2.5 (1.3, 5.8) | 2.3 (1.1, 5.1) | 3.4 (1.7, 8.8) | <0.001 |
eGFR, mL/min/1.73 m2, median (IQR) | 79 (21.4) | 80 (21) | 75.5 (22.3) | <0.001 |
Troponin I, ng/mL, median (IQR) | 0 (0, 0.1) | 0 (0, 0) | 0.6 (0.1, 3.5) | <0.001 |
Total Cholesterol, mg/dL, mean (SD) | 199.2 (49.1) | 197.6 (48.7) | 205 (50.1) | 0.013 |
LDL Cholesterol, mg/dL, mean (SD) | 119.9 (41.9) | 117.2 (41) | 129.6 (43.8) | <0.001 |
HDL Cholesterol, mg/dL, mean (SD) | 50.5 (15.3) | 51.4 (15.6) | 47.6 (3.8) | <0.001 |