Figure 3

Stereochemistry of omega-3 epoxidation of EPA by candidate CYP isoforms. (A) Chemical structures of 17,18-EpETE stereoisomers. (B) Chiral analysis of 17,18-EpETE by LC-MS/MS. Representative chiral analysis illustrating the stereoselectivity of omega-3 epoxidation by BM-3 or mouse CYP isoforms as indicated.