Figure 1 | Scientific Reports

Figure 1

From: Characterization of different bubble formulations for blood-brain barrier opening using a focused ultrasound system with acoustic feedback control

Figure 1

(a) Components of the acoustic feedback control system used in this study. (b) in-vitro tube phantom (c) in-vivo setup. The output signal to the transducer is controlled via computer. The acoustic emissions from stimulated microbubbles are measured with a confocal hydrophone and digitized by the computer. The frequency spectrum of the acoustic emissions is analyzed and the output signal to the transducer is adjusted based on the control algorithm. For the in-vitro study, a single tube phantom was used to evaluate the bubble response. A rat model was used for the in-vivo study.

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