Table 2 Differentially expressed miRNAs in low-grade dysplastic nodule vs healthy patient’s tissue samples (FDR < 0.05).
microRNA ID | Chromosome | Fold change | FDR |
|---|---|---|---|
hsa-miR-141-3p | 12 | 625.50 | 7.60E-04 |
hsa-miR-101-3p | 1 | 208.06 | 7.45E-06 |
hsa-mir-22 | 17 | 111.76 | 6.50E-10 |
hsa-mir-16-1 | 13 | 60.69 | 1.53E-05 |
hsa-mir-486-2 | 8 | 34.93 | 7.48E-06 |
hsa-miR-192-5p | 11 | 34.41 | 2.10E-06 |
hsa-mir-150 | 19 | 33.64 | 2.15E-04 |
hsa-miR-199a-3p | 1 | 32.48 | 8.85E-04 |
hsa-mir-19b-2 | X | 32.27 | 4.61E-06 |
hsa-miR-15a-5p | 13 | 26.71 | 1.98E-03 |
hsa-mir-10b | 2 | 26.66 | 7.48E-06 |
hsa-mir-181c | 19 | 26.55 | 7.45E-06 |
hsa-mir-181a-1 | 1 | 23.72 | 9.13E-06 |
hsa-mir-130a | 11 | 22.38 | 4.29E-05 |
hsa-miR-424-5p | X | 21.67 | 1.24E-04 |
hsa-let-7f-1 | 9 | 20.45 | 8.44E-05 |
hsa-mir-186 | 1 | 15.49 | 7.48E-06 |
hsa-miR-30a-5p | 6 | 15.34 | 1.37E-03 |
hsa-miR-23b-3p | 9 | 13.80 | 7.60E-04 |
hsa-mir-26a-1 | 3 | 11.20 | 1.99E-03 |
hsa-miR-1307-5p | 10 | 10.97 | 4.06E-02 |
hsa-mir-181b-1 | 1 | 10.53 | 5.98E-05 |
hsa-mir-92a-1 | 13 | 9.89 | 1.51E-04 |
hsa-miR-182-5p | 7 | 9.56 | 2.65E-02 |
hsa-mir-10a | 17 | 9.26 | 2.38E-04 |
hsa-mir-26a-2 | 12 | 8.35 | 8.27E-03 |
hsa-mir-191 | 3 | 8.25 | 2.67E-03 |
hsa-mir-92a-2 | X | 7.75 | 1.55E-03 |
hsa-mir-340 | 5 | 7.19 | 2.26E-03 |
hsa-miR-126-5p | 9 | 6.67 | 6.16E-03 |
hsa-miR-29c-3p | 1 | 6.49 | 9.39E-04 |
hsa-mir-16-2 | 3 | 6.39 | 3.99E-02 |
hsa-miR-127-3p | 14 | 6.04 | 3.77E-03 |
hsa-mir-19a | 13 | 5.91 | 2.26E-03 |
hsa-mir-30b | 8 | 5.51 | 1.27E-02 |
hsa-mir-155 | 21 | 5.47 | 1.70E-02 |
hsa-mir-100 | 11 | 5.34 | 5.61E-04 |
hsa-miR-10b-5p | 2 | 5.12 | 4.41E-03 |
hsa-mir-145 | 5 | 4.71 | 8.60E-03 |
hsa-let-7d | 9 | 4.66 | 2.23E-02 |
hsa-miR-320a | 8 | 4.27 | 2.86E-03 |
hsa-mir-181b-2 | 9 | 3.70 | 1.65E-02 |
hsa-mir-532 | X | 3.63 | 4.22E-02 |
hsa-mir-125b-1 | 11 | 3.18 | 1.70E-02 |
hsa-mir-34a | 1 | 2.94 | 4.06E-02 |
hsa-mir-193b | 16 | 2.45 | 4.20E-02 |
hsa-miR-200a-3p | 1 | −1.78 | 4.37E-02 |
hsa-let-7i-5p | 12 | −1.78 | 4.66E-02 |
hsa-miR-215-5p | 1 | −1.96 | 3.38E-02 |
hsa-mir-455 | 9 | −2.03 | 4.12E-02 |
hsa-mir-21 | 17 | −2.08 | 2.65E-02 |
hsa-let-7e-5p | 19 | −2.10 | 3.33E-02 |
hsa-mir-3120 | 1 | −2.20 | 3.66E-02 |
hsa-miR-92a-3p | 13 | −2.21 | 1.74E-02 |
hsa-mir-101-1 | 1 | −2.22 | 3.72E-02 |
hsa-mir-99a | 21 | −2.28 | 1.74E-02 |
hsa-mir-103a-1 | 5 | −2.29 | 2.11E-02 |
hsa-mir-224 | X | −2.34 | 3.22E-02 |
hsa-mir-106b | 7 | −2.34 | 1.61E-02 |
hsa-mir-140 | 16 | −3.01 | 6.10E-03 |
hsa-mir-320a | 8 | −3.02 | 3.79E-03 |
hsa-mir-23b | 9 | −3.12 | 7.86E-03 |
hsa-mir-144 | 17 | −3.19 | 4.12E-02 |
hsa-mir-152 | 17 | −3.28 | 2.51E-03 |
hsa-mir-125b-2 | 21 | −3.47 | 4.41E-03 |
hsa-miR-340-5p | 5 | −3.52 | 2.16E-03 |
hsa-miR-148a-3p | 7 | −4.16 | 3.07E-03 |
hsa-miR-148b-3p | 12 | −4.20 | 6.24E-03 |
hsa-mir-17 | 13 | −4.21 | 1.70E-03 |
hsa-miR-423-3p | 17 | −4.43 | 4.41E-03 |
hsa-mir-3607 | 5 | −4.44 | 1.60E-03 |
hsa-miR-93-5p | 7 | −4.74 | 7.05E-04 |
hsa-mir-126 | 9 | −4.75 | 5.55E-04 |
hsa-mir-3653 | 22 | −4.81 | 1.33E-04 |
hsa-miR-126-3p | 9 | −4.89 | 2.43E-04 |
hsa-mir-23a | 19 | −5.30 | 1.44E-03 |
hsa-miR-24-3p | 19 | −5.44 | 2.26E-03 |
hsa-let-7a-5p | 11 | −5.53 | 7.60E-04 |
hsa-miR-139-5p | 11 | −5.53 | 3.98E-04 |
hsa-mir-3591 | 18 | −6.30 | 2.41E-04 |
hsa-mir-199a-2 | 1 | −6.72 | 1.77E-04 |
hsa-let-7b-5p | 22 | −6.81 | 8.14E-04 |
hsa-mir-101-2 | 9 | −6.99 | 2.88E-04 |
hsa-mir-378a | 5 | −7.06 | 5.82E-05 |
hsa-miR-100-5p | 11 | −7.71 | 1.06E-05 |
hsa-miR-128-3p | 2 | −8.01 | 5.61E-04 |
hsa-mir-194-2 | 11 | −8.52 | 3.03E-04 |
hsa-let-7d-5p | 9 | −10.76 | 9.51E-03 |
hsa-miR-450a-5p | X | −12.31 | 2.38E-05 |
hsa-miR-210-3p | 11 | −12.69 | 1.77E-05 |
hsa-miR-152-3p | 17 | −14.35 | 2.06E-05 |
hsa-miR-532-5p | X | −15.17 | 3.77E-03 |
hsa-mir-424 | X | −15.74 | 1.47E-05 |
hsa-mir-27b | 9 | −17.77 | 7.48E-06 |
hsa-let-7c-5p | 21 | −19.23 | 1.62E-03 |
hsa-miR-125b-5p | 11 | −20.94 | 1.17E-05 |
hsa-miR-99a-5p | 21 | −27.01 | 4.07E-08 |
hsa-mir-103a-2 | 20 | −28.04 | 4.82E-06 |
hsa-miR-185-5p | 22 | −68.06 | 2.60E-08 |
hsa-miR-374a-5p | X | −69.55 | 4.61E-06 |
hsa-let-7g-5p | 3 | −77.05 | 4.07E-08 |
hsa-miR-30c-5p | 1 | −77.77 | 1.33E-04 |
hsa-miR-122-5p | 18 | −80.83 | 4.82E-06 |
hsa-miR-361-3p | X | −94.56 | 3.30E-05 |
hsa-miR-378c | 10 | −103.67 | 5.71E-05 |
hsa-miR-451a | 17 | −513.04 | 2.05E-06 |