Figure 1 | Scientific Reports

Figure 1

From: Development and validation of a LC-MS/MS assay for pharmacokinetic studies of complement C5a receptor antagonists PMX53 and PMX205 in mice

Figure 1

HPLC-MS/MS of PMX53 and PMX205: Product ion MS/MS scan spectra and relative intensities of fragment ions following positive (+2) electrospray ionization of PMX53 (m/z 448.6) (A) and PMX205 (m/z 420.2) (B). Developed MS method under multiple reaction monitoring mode of mass spectrometer combined with liquid chromatography gradient and flow rate conditions (C) for fragment ions resulted HPLC-MS/MS chromatograms of analytes as represented by overlayed chromatograms of complement C5a receptor 1 antagonists PMX53 and PMX205 (D).

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