Figure 4
P75NTR expression in lung cancers and normal lung tissues. (A–F) Immunohistochemical detection of p75NTR, representative pictures are shown for normal tissue (A), squamous cell carcinoma (B–D), adenocarcinoma (E) and small cell cancer (F). Scale = 50 μm. (G) p75NTR staining intensities were significantly higher in squamous cell, adenocarcinoma and small cell cancers. Corresponding median h-scores are presented in Table 1. The box limits indicate the interquartile range (IQR) with the whiskers extending 1.5 times the IQR from the 25th and 75th percentiles (outliers are represented by dots) (*p < 0.0001 in multiple logistic regression model). (H) ROC curve for p75NTR staining intensity level in lung cancers versus normal tissues. The area under the curve was 0.83 (95% CI 0.79 to 0.88).
