Figure 3

Relative accumulation levels of skin metabolites (from frogs grouped by sampling period) associated with key cellular systems (A) Biosynthesis, (B) Degradation, (C) Energy, and (D) relative accumulation data for tricarboxylic acid cycle subsystem intermediates. Large dots represent mean data values for relevant metabolites involved in various subsystems, and small dots represent individual metabolite values. Vertical axis represents normalized relative metabolite accumulation values. Solid colour bars provide the cumulative sum of data values for relevant metabolites, and are more pronounced where many metabolites make a consistent contribution to change within a subsystem.