Figure 2

CTGF delivery via fibrin gel induced recruitment of syMSCs into meniscus defects at day 1 (a), followed by forming matrix by day 7 (b). HNA staining further showed the recruited syMSCs (c) in the intermediate fibrous tissues at 10 days, as confirmed by H&E and Masson’s Trichrome staining (d,c). With fibrin alone without CTGF, neither cell recruitment nor tissue integration was observed (f–h). Scale = 200 µm.