Table 2 ly101-4B treated cells.
Pathway ID | Downregulated biological process | Observed genes | FDR |
|---|---|---|---|
GO.0000278 | mitotic cell cycle | 73 | 1.46e-59 |
GO.0007049 | cell cycle | 80 | 4.09e-54 |
GO.0022402 | cell cycle process | 72 | 1.01e-51 |
GO.1903047 | mitotic cell cycle process | 64 | 8.23e-51 |
GO.0006259 | DNA metabolic process | 54 | 3.38e-39 |
GO.0051276 | chromosome organization | 57 | 1.03e-37 |
GO.0051301 | cell division | 41 | 3.16e-30 |
GO.0044770 | cell cycle phase transition | 36 | 4.36e-30 |
GO.0022616 | DNA strand elongation | 19 | 1.92e-29 |
GO.0006260 | DNA replication | 30 | 4.43e-28 |
GO.0006271 | DNA strand elongation involved in DNA replication | 18 | 6.24e-28 |
GO.0007067 | mitotic nuclear division | 35 | 7.08e-28 |
GO.0044772 | mitotic cell cycle phase transition | 34 | 8.98e-28 |
GO.0006281 | DNA repair | 36 | 4.7e-26 |
GO.0006996 | organelle organization | 75 | 4.7e-26 |
GO.0000280 | nuclear division | 36 | 6.25e-26 |
GO.0006974 | cellular response to DNA damage stimulus | 42 | 1.52e-25 |
GO.0090304 | nucleic acid metabolic process | 80 | 1.77e-20 |
GO.0006310 | DNA recombination | 24 | 2.16e-20 |
GO.1902589 | single-organism organelle organization | 56 | 2.2e-19 |
GO.0006261 | DNA-dependent DNA replication | 18 | 4.59e-19 |
GO.0033554 | cellular response to stress | 51 | 5.4e-19 |
GO.0006139 | nucleobase-containing compound metabolic process | 82 | 6.98e-19 |
GO.0046483 | heterocycle metabolic process | 83 | 1.97e-18 |
GO.0000819 | sister chromatid segregation | 17 | 5.17e-18 |
GO.1901360 | organic cyclic compound metabolic process | 84 | 8.65e-18 |
GO.0071840 | cellular component organization or biogenesis | 83 | 1.18e-17 |
GO.0051726 | regulation of cell cycle | 39 | 1.19e-17 |
GO.0016043 | cellular component organization | 81 | 5.1e-17 |
GO.0000070 | mitotic sister chromatid segregation | 15 | 1.17e-15 |
GO.0034641 | cellular nitrogen compound metabolic process | 83 | 1.2e-15 |
GO.0007059 | chromosome segregation | 20 | 1.58e-15 |
GO.0033260 | nuclear DNA replication | 11 | 3.39e-15 |
GO.0098813 | nuclear chromosome segregation | 17 | 4.42e-15 |
GO.0000082 | G1/S transition of mitotic cell cycle | 19 | 6.44e-15 |