Table 1 Peptide sequences of phage clones binding to FRα in random twelve peptide library.

From: Identification of a peptide for folate receptor alpha by phage display and its tumor targeting activity in ovary cancer xenograft

Clones

Peptide Sequence

A3

Leu-Gly-Ile-Ser-Ala-Thr-Asn-Ala-Tyr-Ala-Arg-His

A4

Phe-Ser-Gln-Ala-Thr-Gly-Arg-Ser-Pro-Thr-Thr-Leu

A7

Ala-Ser-Val-Leu-Asp-Tyr-Lys-Gly-Phe-Phe-Gln-Arg

A12

Thr-Ala-Ala-Gln-Trp-Phe-Pro-Ser-Leu-Ser-Asn-Asn

B1

Asn-Trp-Gln-Pro-Thr-Ala-Gly-Leu-Lys-Pro-Leu-His

B7

Trp-Ser-Ala-Ala-Thr-Val-Pro-Arg-Gly-Phe-His-Ala

B8/H1/G4

Gly-Ala-Leu-Leu-Pro-Ser-Met-Asn-Lys-Gly-His-Trp

C1

Ser-Asn-Ser-Asp-Ala-Tyr-Ala-Leu-Gln-Phe-Leu-Arg

C7

Met-His-Thr-Ala-Pro-Gly-Trp-Gly-Tyr-Arg-Leu-Ser

E9

Phe-Phe-Pro-Leu-Thr-Phe-Pro-Trp-Thr-Tyr-Tyr-Asp

G1/G10

Ser-Gly-Val-Tyr-Lys-Val-Ala-Tyr-Asp-Trp-Gln-His

G9, D5

Val-His-Trp-Asp-Phe-Arg-Gln-Trp-Trp-Gln-Pro-Ser

G8

Tyr-Thr-Asn-Pro-Tyr-Tyr-Ser-Ser-His-Thr-Arg-Asn

G12

Met-Asn-Pro-Tyr-Pro-Arg-Thr-Pro-Trp-Pro-His-Val

H11

Arg-Gly-Met-Asp-Thr-Leu-Trp-His-His-Ala-Tyr-His

  1. 20 clones with the highest ELISA abortion values were sequenced to determine the amino acid sequences of the displayed peptides. 15 clones with individual peptide sequence were identified.