Figure 2 | Scientific Reports

Figure 2

From: Prostate-Specific Membrane Antigen-Targeted Site-Directed Antibody-Conjugated Apoferritin Nanovehicle Favorably Influences In Vivo Side Effects of Doxorubicin

Figure 2

The attenuation of s.c. murine LNCaP xenografts treated with DOX/APODOX/APODOX-anti-PSMA. (a) Schematic depiction of experimental workflow beginning with the LNCaP cells (5 × 106) s.c. inoculation. The schematics of mouse and syringe were adopted under General Public Licence from pixabay.com. (b) Average weight of mice determined over the course of experiment with the weight at the start of experiment designated as 100%. (c) Changes in tumor size during the experiment. (i) 3D reconstruction of tumors. (ii) Changes in tumor volumes compared to the volume at the start of experiment. The values are expressed as means ± standard deviations of independent triplicates. *Indicate statistically significant differences (p < 0.05) when comparing treatments with control (saline).

Back to article page