Table 1 Studies assessing repeated iTBS.

Gamboa²⁴

(n = 10)

• 80% AMT, 600 pulses

• Single

• 2 mins;

• 5 mins;

• 20 mins; 2 blocks

• MEPs (1 mV; mono, PA)

↑ MEPs (single)

↑ MEPs (2 mins)

↔ MEPs (5 mins)

↔ MEPs (20 mins)

↔ MEPs (2 mins)*

↓ MEPs (5 mins)*

↓ MEPs (20 mins)*

Murakami²⁵

(n = 9, 80% AMT; n = 8, 70% AMT)

• 80% AMT (both blocks), 600 pulses

• 70% AMT (first block) 80% AMT (second block)

• Single

• 15 mins; 2 blocks

• MEPs (1 mV, 90–140% S1mV; mono, PA)

• SICI (2 ms ISI; CS = 70–100% AMT; TS = S1mV)

↑ MEPs (single; 80% AMT)*

↓ MEPs (15 mins; 80% AMT)*

↔ SICI (single; 80% AMT)*

↓ SICI (15 mins; 80% AMT)*

↑ MEPs (single; 80% AMT)*

↔ MEPs (15 mins; 70% AMT)*

↔ SICI (single; 70% AMT)*

↔ SICI (15 mins; 70% AMT)*

Mastroeni²⁸

(n = 29)

• 80% AMT, 600 pulses

• Single

• 30 mins; 2 blocks

• MEPs (0.5 mV; mono, PA; bi AP-PA)

↑ MEPs mono (single)

↑ MEPs bi (single)

↑ MEPs mono (30 mins)

↑ MEPs bi (30 mins)

↔ MEPs mono (30 mins)*

↔ MEPs bi (30 mins)*

Nettekoven^26,29

(n = 16)

• 70% RMT, 600 pulses

• Single,

• 15 mins; 3 blocks

• MEPs (90–150% RMT; mono, PA)

↑ MEPs (single)

↑ MEPs (15 mins; 2 blocks)

↑ MEPs (15 mins; 3 blocks)

↔ MEPs (15 mins; 2 blocks)*

↑ MEPs (15 mins; 3 blocks)*

Opie²⁷

(n = 16)

• 70% RMT, 600 pulses

• Single

• 10 mins; 2 blocks

• MEPs (1 mV; mono, PA)

 ↔ MEPs (single)

↑ MEPs (10 mins)

↑ MEPs (10 mins)*