Figure 3 | Scientific Reports

Figure 3

From: Intermittent fasting uncovers and rescues cognitive phenotypes in PTEN neuronal haploinsufficient mice

Figure 3

Intermittent fasting increased the exploration of open arms in HT animals in the elevated plus maze assay. (a) Total distance travelled, two-way ANOVA followed by Holm-Sidak’s post hoc test, P > 0.05, n = 16 (C/HT, IF/HT), 18 (C/WT), and 20 (IF/WT); (b) latency to first entry in open arms, Kruskal-Wallis test, *P ≤ 0.05, n = 16 (C/HT, IF/HT), 18 (C/WT), and 20 (IF/WT); (c) number of entries in open arms, Kruskal-Wallis test, *P ≤ 0.05, n = 16 (C/HT, IF/HT), 18 (C/WT), and 20 (IF/WT); (d) number of entries in central area, Kruskal-Wallis test, P > 0.05, n = 16 (C/HT, IF/HT), 18 (C/WT), and 20 (IF/WT); (e) number of entries in closed arms, Kruskal-Wallis test, P > 0.05, n = 16 (C/HT, IF/HT), 18 (C/WT), and 20 (IF/WT); (f) representative heat map plot for animal movement in the apparatus.

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