Figure 9

Photograph of mouse left ear pinna, (a) and (h) are images of the blood vessel under OCT detection, the red line denotes the location of the acquired B-scan. (b–f) The OCT intensity images of before and after 5, 10, 20, 30 mins as intravenous nanocrystals by circulation, respectively. (g) Value of OCT signal changing with the nanocrystal cycling in the blood vessels of mice. (i–k) OCT intensity images of different intravenous nanocrystal concentrations (1 mg/mL, 2 mg/mL and 5 mg/mL, respectively) by the same circulation time. (l) The OCT intensity of the intravenous nanocrystal concentration enhances in blood vessels.