Table 4 Odds ratiosa (95% CIs) of impaired LV relaxation according to the presence of NSSTTA in clinically relevant subgroups.
Subgroup | Without NSSTTA | With NSSTTA | P for interaction |
|---|---|---|---|
Sex | 0.36 | ||
Female (n = 21,694) | 1.00 (reference) | 1.75 (1.31–2.36) | |
Male (m = 53,282) | 1.00 (reference) | 1.51 (1.26–1.80) | |
Age | 0.62 | ||
<50 years (n = 66,976) | 1.00 (reference) | 1.74 (1.48–2.04) | |
≥50 years (n = 8,000) | 1.00 (reference) | 1.62 (1.14–2.32) | |
Current smoker | 0.18 | ||
No (n = 51,677) | 1.00 (reference) | 1.40 (1.16–1.70) | |
Yes (n = 16,818) | 1.00 (reference) | 1.84 (1.38–2.45) | |
Alcohol intake | 0.90 | ||
<20 g/day (n = 52,816) | 1.00 (reference) | 1.53 (1.27–1.85) | |
≥20 g/day (n = 17,930) | 1.00 (reference) | 1.60 (1.21–2.13) | |
HEPA | 0.14 | ||
No (n = 62,063) | 1.00 (reference) | 1.66 (1.40–1.97) | |
Yes (n = 11,253) | 1.00 (reference) | 1.22 (0.87–1.72) | |
BMI | 0.46 | ||
<25 kg/m2 (n = 49,261) | 1.00 (reference) | 1.65 (1.35–2.02) | |
≥25 kg/m2 (n = 25,715) | 1.00 (reference) | 1.48 (1.18–1.86) | |
HOMA-IR | 0.08 | ||
<2.5 (n = 64,161) | 1.00 (reference) | 1.63 (1.37–1.92) | |
≥2.5 (n = 10,707) | 1.00 (reference) | 1.29 (0.91–1.83) | |
hsCRP | 0.79 | ||
<1.0 mg/l (n = 53,493) | 1.00 (reference) | 1.52 (1.26–1.84) | |
≥1.0 mg/l (n = 18,283) | 1.00 (reference) | 1.61 (1.21–2.13) | |
Diabetes | 0.57 | ||
No (n = 71,283) | 1.00 (reference) | 1.56 (1.33–1.83) | |
Yes (n = 3,693) | 1.00 (reference) | 1.40 (0.80–2.45) | |
Hypertension | 0.91 | ||
No (n = 64,570) | 1.00 (reference) | 1.56 (1.31–1.86) | |
Yes (n = 10,406) | 1.00 (reference) | 1.52 (1.14–2.04) | |
Framingham Risk Score | 0.02 | ||
<10% (n = 61,651) | 1.00 (reference) | 1.39 (1.17–1.66) | |
≥10% (n = 6,844) | 1.00 (reference) | 2.46 (1.61–3.75) |
