Figure 3
The lipidomic analysis of epididymal white adipose tissue (eWAT) of mice fed various diets. Mice were fed AIN93G diet (Control or Ctrl), or a Western diet (WD) or a Western diet supplemented with 0.1% curcumin (WD + Cur) for 16 weeks. The lipidomic analysis of eWAT was performed using supercritical fluid chromatography/tandem mass spectrometry. (a) The principal component analysis of the lipidome, (b) heat map of lipid species and (c) contents of lipid classes in eWAT. Values are expressed as mean ± SD for each group (n = 5). Colour scales for the heat map signify the levels of each lipid. Data were log2 transformed and the mean value of five biological replicates is presented. CE, cholesterol ester; TAG, triacylglycerol; FFA, free fatty acid; DAG, diacylglycerol; PC, phosphatidylcholine; PE, phosphatidylethanolamine; PEp, plasmenyl-phosphatidylethanolamine (phosphatidylethanolamine plasmalogen); LPC, lysophosphatidylcholine; PI, phosphatidylinositol; PS, phosphatidylserine; SM, sphingomyelin; LPE, lysophosphatidylethanolamine; PCe, plasmanyl-phosphatidylcholine; PCp, plasmenyl-phosphatidylcholine (PC plasmalogen); PG, phosphatidylglycerol; Cer, ceramide and MAG, monoacylglycerol. Also refer Table S6.
