Table 1 Curcumin reduced the levels of blood glucose and lipid peroxidation markers in Western diet-induced obese mice.

	Control diet	Western diet	Western diet + 0.1% curcumin
Body weight (g)	41.51 ± 1.55^a	47.49 ± 0.79^b	44.93 ± 0.83^ab
Liver weight (g)	1.62 ± 0.07^a	3.44 ± 0.20^b	3.08 ± 0.25^ab
Kidney weight (g)	0.37 ± 0.02	0.38 ± 0.01	0.39 ± 0.01
Pancreas weight (g)	0.33 ± 0.03	0.33 ± 0.02	0.34 ± 0.02
(eWAT (g/mouse)) Visceral fat (g/mouse)	(2.09 ± 0.18) 3.71 ± 0.33	(2.42 ± 0.08) 4.48 ± 0.22	(2.45 ± 0.07) 4.17 ± 0.17
Malondialdehyde in livers (nmol/mg protein)	1.96 ± 0.15^a	3.42 ± 0.54^b	0.74 ± 0.16^c
Malondialdehyde in eWAT (nmol/mg protein)	4.38 ± 0.20^a	9.02 ± 0.83^b	3.85 ± 0.42^a
Blood glucose (mg/dL)	152 ± 7^a	201 ± 6^b	162 ± 8^a
Plasma insulin (ng/mL)	2.07 ± 0.49	4.02 ± 0.74	3.08 ± 0.42
Plasma cholesterol (mg/dL)	83.7 ± 10.3^a	208.9 ± 9.8^b	211.4 ± 14.9^b
Plasma triglyceride (mg/dL)	66.2 ± 4.9^a	55.2 ± 4.2^ab	46.1 ± 1.2^b
Plasma NEFA (mEq/dL)	0.68 ± 0.11^a	0.54 ± 0.05^ab	0.34 ± 0.03^b
Plasma 8-isoprostane (pg/mL)	166.1 ± 18.5^a	341.3 ± 53.9^b	245.5 ± 26.7^ab
Plasma TNF-α (pg/mL)	3.63 ± 0.44	12.76 ± 5.97	6.10 ± 1.14
Plasma IFN-γ (pg/mL)	4.60 ± 0.94	48.59 ± 26.25	18.89 ± 11.04
Plasma leptin (ng/mL)	3.69 ± 0.83^ab	5.38 ± 0.46^a	3.35 ± 0.32^b

C57BL/6 J mice were fed the control AIN93G diet or a Western diet supplemented with either 0% or 0.1% curcumin for 18 weeks. Values are expressed as mean ± SEM (8–9 mice/group). Different superscripts (a, b, c) indicate significant differences (P < 0.05, two-sided).

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